tag:blogger.com,1999:blog-5472921328078253036.post6088931407065259180..comments2024-01-27T19:53:22.965-08:00Comments on Current Research into Cures for Type-1 Diabetes: Perle Biosciences Starts a Phase-II Trial Of A Combo CureJoshua Levyhttp://www.blogger.com/profile/05300553471793001620noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-5472921328078253036.post-29230569265869886922015-12-19T09:50:41.944-08:002015-12-19T09:50:41.944-08:00Few people developed kidney diseaseFew people developed kidney diseaseAnonymoushttps://www.blogger.com/profile/11815798121527240358noreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-21413482708279339512015-12-05T12:19:34.756-08:002015-12-05T12:19:34.756-08:00The email that I got was sent on Aug 27th. It ref...The email that I got was sent on Aug 27th. It referred to "proton pump inhibitor" (did not include the exact drug), and was at 120mg per day for adults. That is all that I know. The confusion that you describe is entirely possible. Joshua Levyhttps://www.blogger.com/profile/05300553471793001620noreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-51215843466667455942015-12-05T11:54:00.701-08:002015-12-05T11:54:00.701-08:00Thanks for your reply, Joshua. I'm interested ...Thanks for your reply, Joshua. I'm interested in ascertaining what the Omeprazole dosage will be - did Perle's email say the Omeprazole dosage will be 120mg a day?<br /><br />As you explained, the original study called for 120mg daily of Lansoprazole. When the study changed the proton pump inhibitor to Omeprazole, the dosage notation was deleted by Perle on the study's US Trial Registry (see archived history of changes 6/26/15). The Omeprazole dosage does not appear on the study's European Trial Registry either.<br /><br />My suspicion is that since proton pump inhibitor dosages are not necessarily equivalent (see http://www.globalrph.com/proton_pump_inhibitors.htm for the Lansoprazole/Omeprazole comparison), the Omeprazole dosage may be different from (and significantly less than) that of the Lansoprazole.<br /><br />Thanks again for your help.Theresa Morihttps://www.blogger.com/profile/07307464290800200749noreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-62970346727982693022015-12-04T19:25:46.075-08:002015-12-04T19:25:46.075-08:00The dosing information was sent to me via email, b...The dosing information was sent to me via email, by Perle Biosciences. So it would be "per comm" (personal communication). --JoshuaJoshua Levyhttps://www.blogger.com/profile/05300553471793001620noreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-50268661838759568642015-12-04T07:11:48.688-08:002015-12-04T07:11:48.688-08:00Where did you find the dosing information? I don&#...Where did you find the dosing information? I don't see it on the registry or referenced articles or studies. Many thanks for all your hard work on this blog!Theresa Morihttps://www.blogger.com/profile/07307464290800200749noreply@blogger.com