tag:blogger.com,1999:blog-5472921328078253036.post7028000035543434793..comments2024-01-27T19:53:22.965-08:00Comments on Current Research into Cures for Type-1 Diabetes: El-Khatib's Group Announces Phase-I ResultsJoshua Levyhttp://www.blogger.com/profile/05300553471793001620noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-5472921328078253036.post-49015039402326490962010-05-26T22:49:15.502-07:002010-05-26T22:49:15.502-07:00You would have to ask each researcher why they cho...You would have to ask each researcher why they chose time rather than measuring C-peptide. I can't speak for each of them. <br /><br />However, my guess is this: very few people with type-1 for more than a year generate much of their own insulin (measured by c-peptide). Maybe the number is 1 in 50 or 1 in 100 or 1 in 200. Something like that. And the researchers don't want to test 100 people just to find one who can be in the trial. (Think of how many you would need to test to fill even a 40 person trial!) Better to just limit it by year, so everyone knows who can join and who can not, without special testing. At least that is my best guess. And you can't say "1 year or generating c-peptides" because then you basically have two different groups of people in one trial.<br /><br />Joshua LevyJoshua Levyhttps://www.blogger.com/profile/05300553471793001620noreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-37111206765541003422010-05-23T05:06:30.575-07:002010-05-23T05:06:30.575-07:00Hi Joshua,
All the recent phase three trails are ...Hi Joshua,<br /><br />All the recent phase three trails are for honeymooners. There could be possibility that people with long standing diabetes have more beta mass left. Why this is not linked to C peptide levels, rather than period of diagnosis. Can you explain.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-69621967449450037572010-05-21T02:09:38.514-07:002010-05-21T02:09:38.514-07:00I always thought the use of AP as an interim step ...I always thought the use of AP as an interim step while getting a medical cure. So I think a big step forward. Thanks for the news and sorry for my English (I'm using the Google translator). <br />RegardsAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-83347360970831291452010-05-19T14:38:11.688-07:002010-05-19T14:38:11.688-07:00Thanks for the info although I am not a big fan of...Thanks for the info although I am not a big fan of the AP.katerinahttps://www.blogger.com/profile/03041648390107806818noreply@blogger.com