tag:blogger.com,1999:blog-5472921328078253036.post5265603507907807045..comments2024-01-27T19:53:22.965-08:00Comments on Current Research into Cures for Type-1 Diabetes: Glucagon / Leptin type-1 "Cure" in the NewsJoshua Levyhttp://www.blogger.com/profile/05300553471793001620noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-5472921328078253036.post-85606610912908036392011-02-23T10:42:39.938-08:002011-02-23T10:42:39.938-08:00Thanks for unpacking speculation around this study...Thanks for unpacking speculation around this study and providing more context/info! This study raises a lot of questions, but even diabetes media outlets have just been passing along the same synopsis of the study without additional comment. Really useful post.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-65110615633162056912011-02-21T16:03:26.249-08:002011-02-21T16:03:26.249-08:00Unfortunately, the authors of this study rather ir...Unfortunately, the authors of this study rather irresponsibly remarked at the end that it might show the route to a cure for humans, and the news media picked up on that, thus intensifying the confusion. The simple fact is that type 1 diabetic humans lose weight without injected insulin, while the mice in this experiment could maintain normoglycemia and normal weight with mere glucagon receptor suppression but without exogenous insulin. From millions of type 1 human diabetics who all lost weight before starting on insulin injections, we know that these mice results are totally irrelevent to human diabetes.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5472921328078253036.post-8215472805975114982011-01-31T04:35:18.709-08:002011-01-31T04:35:18.709-08:00Hi, Josh! There is a reason why the pancreas remov...Hi, Josh! There is a reason why the pancreas removal people are not the same as the test mice. The pancreas removal folks do not make glucagon. The mice made glucagon, but their cells were engineered to not respond to it.<br /><br />Thanks so much for posting this! I cannot even understand the skepticism by other T1s. This new mechanism may change everything we knew and may gt us on the right path to a cure.Sears Homes of Chicagolandhttps://www.blogger.com/profile/06852344154514348451noreply@blogger.com