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Thursday, October 1, 2026

Tolimidone (MTX228) Starts A Phase-IIΔ Clinical Trial on Honeymooners

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These researchers are testing Tolimidone (also known as MTX228), which has a long history.  It was developed by Pfizer as a treatment for ga...
Thursday, September 17, 2026

OPT101 Starts a Phase-II Clinical Trial

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OPT101 is a small peptide (a type of protein) designed to target CD40, which plays a central role in the inflammatory autoimmune response th...
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Saturday, July 4, 2026

Allogeneic CD7-Targeted CAR-T Cell (RD13-02) Starts Second Phase-I Clinical Trial

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RD13-02 uses specially engineered immune cells designed to remove certain immune cells believed to drive the autoimmune attack that damages ...
1 comment:
Tuesday, June 16, 2026

SAB-142 From SAb Biotherapeutics Starts a Phase II Trial (SAFEGUARD)

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Back in April, I blogged about a Phase-II study called "Anti-Thymocyte Globulin and Verapamil Start A Phase-2 Clinical Trial" (NCT...
Thursday, June 4, 2026

Rezpegaldesleukin (or NKTR-358) Starts A Phase-IIΔ Clinical Trial on Honeymooners (RESET T1D)

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A new clinical trial is testing Rezpegaldesleukin, also known as NKTR-358, or REZPEG, as a potential treatment to slow or stop T1D in honeym...
Thursday, May 14, 2026

Phase-I Clinical Trial of Islet Transplantation Into Eye

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Pancreatic islet transplantation is an approach designed to restore the body’s ability to produce insulin by transplanting beta cells (insul...
Thursday, April 30, 2026

Anti-Thymocyte Globulin and Verapamil Start A Phase-2 Clinical Trial

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Researchers at the University of Florida are launching a new Phase 2 clinical trial to evaluate a combination therapy for individuals recent...
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