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Friday, February 6, 2026

Open Letter: Focus On Hidden Transplanted Beta Cells

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An open letter to everyone who cares about research aimed at type 1 diabetes cures. I've been blogging on research aimed at curing type ...
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Friday, January 30, 2026

SAR442970/Brivekimig Starts a Phase IIΔ Trial In Honeymooners (T1D OBTAIN)

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The treatment being tested is called Brivekimig (previously SAR442970). It is a type of biologic drug known as a bispecific nanobody. It is ...
Wednesday, January 7, 2026

Rituximab and Treg Cells Starts a Phase IIΔ Trial In Youth At Risk Of Diabetes

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A new clinical trial is exploring whether two different immune therapies, used alone or in combination, can delay or prevent the onset of  T...
Wednesday, December 17, 2025

Fecal Transplantation Starts A Phase-II Trial (FACT-T1D)

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The Fecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus (FACT-T1D) trial is testing a new approach to treating or curing t...
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Friday, December 5, 2025

CNK-UT009 Cell Therapy Starts A Phase-I Clinical Trial

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CNK-UT009, as tested here, is a one-time infusion of living cells designed to modify the immune system’s behavior.  The idea behind it is th...
Wednesday, October 29, 2025

IMMUNOSTEM starts a Phase-I Clinical Trial in Honeymooners

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IMMUNOSTEM technology refers to using a virus (specifically a lentivirus) to deliver a new gene into cells, which will then produce a specif...
Saturday, September 27, 2025

Results from a Phase-II Clinical Trial of Baricitinib

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Baricitinib works by interfering with signaling pathways inside immune cells, to reduce inflammation and lower the immune system.  It is par...
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