Atrovastatin (much better known as Lipitor) has now finished it's second phase-II trial. The previous trial was unsuccessful, and this trial is unsuccessful, so I think that Lipitor is probably done as a potential cure for type-1 diabetes. You can read my previous blogging here:
This clinical trial started recruiting patients in July 2007, finished collecting data in July 2011, and finished completely in July 2013. It's now been 3 years since that date, and I cannot find a publication reporting on the results of this trial. In my experience trials with successful results are usually published within a year of completion, while those which are unsuccessful often languish for years, unpublished.
Clinical Trial Record: https://clinicaltrials.gov/ct2/show/NCT00529191
The previous Lipitor paper is here:
Conclusion from this previous paper:
Atorvastatin treatment did not significantly preserve beta cell function although there may have been a slower decline of beta-cell function which merits further study.Discussion
The problem of researchers not publishing results from unsuccessful clinical trials has been getting some press recently. For example:
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All the views expressed here are those of Joshua Levy, and nothing here is official JDRF, JDCA, or Tidepool news, views, policies or opinions. My daughter has type-1 diabetes and participates in clinical trials, which might be discussed here. My blog contains a more complete non-conflict of interest statement. Thanks to everyone who helps with the blog.